Congratulations to Sofia Chatzianagnosti on her graduation (BSc in Molecular Biology & Genetics)
Welcome to DarkMatters Group
The DarkMatters Group (head: Assistant Professor Antonios Giannakakis) is part of Gene Expression, Molecular Diagnosis and Modern Therapeutics Lab, that was founded by Professor Raphael Sandaltzopoulos in 2002.
Our group belongs to and operates in Department of Molecular Biology & Genetics (MBG) that was established in 2000 in Alexandroupolis with the vision to become a Leader Institution in Education & Research.
The MBG department is under the Faculty of Health Science School at Democritus University of Thrace (DUTH) that established in July 1973. DUTH is based in Komotini-Greece and has campuses in the Thracian cities of Xanthi, Komotini, Alexandroupoli and Orestiada.
Announcements
26 JUL 2022
26 JUL 2022
Congratulations to Tobias Kedziersk on his graduation (BSc in Molecular Biology & Genetics)
26 JUL 2022
Congratulations to Orfeas Kalamenios on his graduation (BSc in Molecular Biology & Genetics)
14 OCT 2021
Our work on lncRNAs in breastmilk exosomes has now appeared online at the International Journal of Molecular Medicine
24 Sep 2021
Congratulations to Efthymia Vasilina Katsika on her graduation (BSc in Molecular Biology & Genetics)
19 Mar 2021
Congratulations to Androniki Tasiopoulou on her graduation (BSc in Molecular Biology & Genetics)
Research Objectives
High-throughput analysis of non-coding RNAs interactome in both health and disease contexts
Detecting long non-coding RNAs as part of the dark proteome
Deciphering the roles of stress-induced long non-coding RNAs in stress responce and cancer
Involvement of non-coding RNAs in chronic inflammation and autoimmune disorders
Exosome biobanking of biofluids in Multiple Sclerosis (MS) patients
Unravelling the role of long non-coding RNAs in breastmilk exosomes
Tools, Datasets and Biobanks
Tools & Pipelines
We are developing pipelines for high-throughput genomic/transcriptomic NGS data analysis in order to demonstrate them as public available web tools.
Databases
There are no available databases at this time. Our first db is under construction.
Biological Datasets
Our group has obtained access in controlled access datasets like The Cancer Genome Atlas (TCGA) programm with over 11000 sequenced and molecularly characterized cases of primary cancer samples.
Biological Samples
Biological sample collection from multiple sclerosis patients and other autoimmune disorders.
Academic-Research Collaborators
George P. Chrousos
Professor of Pediatrics and Endocrinology Emeritus
University Research Institute of Maternal and Child Health and Precision Medicine, Greece
Artemis Hatzigeorgiou
Professor of Bioinformatics
Department of Electrical and Computer Engineering, University of Thessaly, Greece
Vladimir Kuznetsov
Professor of Urology/Professor of Biochemistry and Molecular Biology
Upstate Medical University, USA
Lesley Probert
Researcher (Professor level)
Laboratory of Molecular Genetics, Hellenic Pasteur Institute, Greece
Michalis Aivaliotis
Associate Professor of Biochemistry
Μedicine Department, Aristotle University of Thessaloniki, Greece
Dimitris Vlackakis
Associate Professor
Agricultural University of Athens, Greece
Industry-Research Collaborators
Paschalis C. Papazilakis
President/CEO
EVROFARMA SA, Greece
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A novel pipeline to enrich formula milk using omics technologies
We aim to perform an extensive comparative analysis of human breastmilk with three locally traded animal milks (domestic sheep, goats and cattle from different regions of Greece). In particular, a high-quality, quantitative and qualitative study will be conducted for the analysis of the membrane and intracellular composition of the major classes of secreted extracellular vesicles and other transported microparticles.
-Develop research infrastructures in academia and the private sector for fingerprinting human breastmilk.
-Discover epigenetic mechanisms of signal transfer through exosome analysis
-Discover novel lncRNAs in breast milk exosomesProject Role: Work-Package Leader
Dr. Giannakis's WP: €120,000
